- Betty: "Get out of my house."
- Cheryl: "Not until you tell me—"
- Betty: "Cheryl, get the hell out of my house before I kill you."
- ―Betty to Cheryl, after the latter accused her sister Polly of killing Jason[src]
The relationship between Cheryl Blossom and Betty Cooper is hard to define, but the two can currently be called rivals, though frenemies may be more accurate. They both care for each other but haven't openly admitted it, therefore they can be seen as friends in denial about their friendship.
Cheryl and Betty met at some point before the start of the series. They share a connection, as Cheryl's now deceased twin brother Jason dated Betty's older sister Polly, and apparently, their relationship did not end on good terms. After her brother's death, Cheryl started to despise Betty and continuously humiliate her whenever she got a chance.
During the previous school year, Betty tried out for the cheer squad but was rejected by Cheryl who claimed Betty was too fat.
Throughout Riverdale Edit
After Archie's father was shot and sent to Riverdale General Hospital, later during the day, Kevin and Betty were discussing about Betty's love life. Their conversation ended when they spotted Cheryl coming into the hospital with a body wrapped in up bandages. They later go to talk to Cheryl to ask her if the body covered in bandages was her mother, which Cheryl confirmed that it was. Informing them that their house burnt down.
A couple days later, Jughead was informed that his father would possibly be spending 20 to 40 years in prison, as Jughead was worried for what would become of his father once his court trail began. He later went to see an attorney named Penny Peabody, who informed Jughead that the only way he could help his fathers case, was to speak to the Blossom Family to get them to make a statement that they don't hold FP accountable for the death of Jason Blossom, stating that they forgive him for his part in the crime committed. Jughead later headed over with Betty to the Thistlehouse, where Cheryl and her mother, Penelope where staying. To convince them to making a statement that would help in FP's case. However, the Blossom's were reluctant to do so, refusing to help Jughead. As Penelope and Cheryl wanted FP to suffer for what happened to Jason. As Betty later pointed out to Cheryl that it wasn't FP who killed her brother, it was her father.
Later, Betty stopped by the girls locker room, as she came by to have a chat with Cheryl. Betty blackmailed Cheryl into testifying on the behalf of her family for FP's court trail, without Jughead knowing about it. As she threatened Cheryl that she would show everyone of the copied footage that was made an kept on Jughead's laptop, of the night her father, Clifford, killing Jason in cold blood. Ashamed by her fathers sins, and how it would impact her and her mother, Cheryl was willing to make her statement to prevent the footage from getting out.
Back at Riverdale High School, in the student lounge, Betty greets Kevin as she spotted him doing some homework. She asks Kevin what happened to him last night, as he told Betty earlier that he was coming over by Veronica's. Kevin later responded to Betty, telling her that he was coming over but something came up. Continuing to resume doing his homework after. However, Betty being Betty, wanted to know what suddenly came up for Kevin, causing him to not being able to hang out with them. Later questioning Kevin if it had something to do with being in the woods. Kevin later responds to Betty's question, as he tells her not to take his comment the wrong way, confronting her, stating that he listened to her for years reminiscing about Archie and now Jughead. Pointing out that she didn't ask him for his permission to date them, later stating that she didn't, since she didn't need it, telling Betty that he didn't need hers either. As Cheryl is seated near them, faced the other direction eavesdropping on their conversation. Betty later tries to talk to Kevin, however, Kevin cut her off before she could say anymore to him, telling Betty that it was none of her business. Packing his things up to leave, as he was annoyed by Betty's presents. Cheryl later approaches Betty, confirming that Kevin has a sex-drive, asking Betty what was the big deal. Which Betty informs Cheryl that with his recent known activities, its putting Kevin in danger, due to recent events that have accured linked to the Black Hood. As Cheryl tries to have Betty understand Kevin's situation.
Later that day, during that night at Pop's, Cheryl spotted Kevin getting ready for another one of his late night jogs. As she suspected that he was headed for the woods again, even though Betty tired to warn him earlier not to go back there until the "Black Hood" was caught. However, Betty and Cheryl later went searching for him, as they caught him through the woods. Which Kevin was surprised to see them there, asking Betty what she was doing there with him. Betty later informed Kevin that she received a phone call from Cheryl earlier to notify her that he was headed towards Fox Forest again. Betty later reminded Kevin that he told her that he wasn't going to go through the woods again. Kevin is upset to see Betty, as she was on his case a lot lately. Asking what she wanted from him, which Betty responds that she wanted him to have more self respect for himself. Which Kevin informs Betty that they've been friends for a long time, but she still had no idea what it was like for him. As he tells her that she acts like they have the same set of options when it comes to dating, which they not. Confronting Betty that she lives in a "pale-pink world of milkshakes and first kisses", with options on who to date such as Archie and Jughead. As Cheryl adds on with the exception when she "Dark Betty", which Kevin agrees with Cheryl as he pointed out when Betty is exploring her BDSM sexuality. As he continued to tell Betty that she was allowed to do those things but he wasn't. Telling Betty that the woods was all he had to meet guys.
- Cheryl: "Tell Veronica about your sister and my dear brother."
- Betty: "Polly and Jason dated."
- Cheryl: "' [scoffs] I wouldn't say "dated"."
- Betty: "It didn't end well."
- Cheryl: "In fact, Jason's probably why your sister had a nervous breakdown and now lives in a group home, isn't it?"
- Betty: "That's what my parents think."
- Cheryl: "What do you have to say about that, Betty? Go ahead, the floor is yours. Whatever you've been dying to spew about Jason and how he treated Polly, unleash it. Destroy me. Tear me a new one. Rip me to shreds. Annihilate me."
- Betty: "I just..."
- Cheryl: "Finally."
- Betty: "I just wanted to say I'm sorry about what happened to Jason. I can't even imagine what you and your family must be going through."
- ―Cheryl tries to provoke Betty[src]